Deuruxolitinib

Overview

Deuruxolitinib is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL4594381).

Patent & exclusivity (US)

Per the FDA Orange Book (1 approved US product), the latest listed US patent on Deuruxolitinib expires 10 Oct 2044 and exclusivity 25 Jul 2029. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

(3R)-3-(2,2,3,3,4,4,5,5-octadeuteriocyclopentyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile

Canonical SMILES

[2H]C1(C(C(C(C1([2H])[2H])([2H])[2H])([2H])[2H])[C@@H](CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3)[2H]

InChIKey

HFNKQEVNSGCOJV-FBXGHSCESA-N