Desmopressin

Overview

Desmopressin is a protein active pharmaceutical ingredient (ChEMBL CHEMBL1429).

API suppliers (13)

Suppliers of Desmopressin evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• PolyPeptide Laboratories (Sweden) ABSweden2 active DMF GMP on record
• TAPI NL BVNetherlands1 active DMF
• ASPEN OSS BVNetherlands1 active DMF GMP on record
• AURO PEPTIDES LTD1 active DMF
• SHILPA PHARMA LIFESCIENCES LTDIndia1 active DMF
• MYLAN LABORATORIES LTD GMP on record
• BACHEM INCSwitzerland GMP on record
• SINOPEP PHARMACEUTICAL INC
• SPECGX LLCUnited States
• Aspen Pharmacare Holdings LimitedSouth AfricaCEP
• Piramal Pharma LimitedIndiaCEP GMP on record
• IAF BIOCHEM INTERNATIONAL INC
• DIOSYNTH BV

EU CEP holders (6)

Companies holding a valid EU Certificate of Suitability (CEP) for Desmopressin, from the EDQM certification database. A CEP holder is a documented EU-market source of the substance — not necessarily the manufacturer — and these are not yet profiled in our directory.

Patent & exclusivity (US)

Per the FDA Orange Book (25 approved US products), the latest listed US patent on Desmopressin expires 3 Apr 2044. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

(2S)-N-[(2R)-1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide

Canonical SMILES

C1C[C@H](N(C1)C(=O)[C@@H]2CSSCCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)C(=O)N[C@H](CCCN=C(N)N)C(=O)NCC(=O)N

InChIKey

NFLWUMRGJYTJIN-PNIOQBSNSA-N