Desmopressin

Overview

Desmopressin is a protein active pharmaceutical ingredient (ChEMBL CHEMBL1429).

API suppliers (12)

Suppliers of Desmopressin backed by a verifiable FDA Type II Drug Master File. Source: FDA quarterly DMF list.

• POLYPEPTIDE LABORATORIES INCUnited States2 active DMF
• TAPI NL BV1 active DMF
• TAPI NL BV1 active DMF
• ASPEN OSS BV1 active DMF
• AURO PEPTIDES LTD1 active DMF
• TAPI NL BV1 active DMF
• SINOPEP PHARMACEUTICAL INC
• IAF BIOCHEM INTERNATIONAL INC
• DIOSYNTH BV
• SPECGX LLCUnited States
• BACHEM INC
• MYLAN LABORATORIES LTD

Patent & exclusivity (US)

Per the FDA Orange Book (26 approved US products), the latest listed US patent on Desmopressin expires 2 Apr 2044. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

(2S)-N-[(2R)-1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide

Canonical SMILES

C1C[C@H](N(C1)C(=O)[C@@H]2CSSCCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)C(=O)N[C@H](CCCN=C(N)N)C(=O)NCC(=O)N

InChIKey

NFLWUMRGJYTJIN-PNIOQBSNSA-N