Dapsone

Overview

Dapsone is an antimicrobial compound used primarily to treat leprosy and dermatitis herpetiformis. It acts as a bacteriostatic agent by inhibiting bacterial synthesis of dihydrofolic acid.

API suppliers (9)

Suppliers of Dapsone backed by a verifiable FDA Type II Drug Master File. Source: FDA quarterly DMF list.

• Macleods Pharmaceuticals Ltd.India2 active DMF
• ALIVUS LIFE SCIENCES LTD1 active DMF
• LUNDBECK PHARMACEUTICALS ITALY SPAItaly1 active DMF
• ALIVUS LIFE SCIENCES LTD1 active DMF
• LUNDBECK PHARMACEUTICALS ITALY SPAItaly1 active DMF
• ALIVUS LIFE SCIENCES LTD1 active DMF
• ATUL LTDIndia1 active DMF
• LUNDBECK PHARMACEUTICALS ITALY SPAItaly1 active DMF
• ATUL LTDIndia1 active DMF

Patent & exclusivity (US)

Per the FDA Orange Book (27 approved US products), the latest listed US patent on Dapsone expires 18 Nov 2033. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

4-(4-aminophenyl)sulfonylaniline

Canonical SMILES

C1=CC(=CC=C1N)S(=O)(=O)C2=CC=C(C=C2)N

InChIKey

MQJKPEGWNLWLTK-UHFFFAOYSA-N

Therapeutic areas