Danicopan
CAS 1903768-17-1Small Molecule
Overview
Danicopan is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL4250860).
Patent & exclusivity (US)
Per the FDA Orange Book (2 approved US products), the latest listed US patent on Danicopan expires 2 Aug 2038 and exclusivity 29 Mar 2031. Generic API sourcing typically opens up once these lapse.
Chemical identity
- IUPAC name
- (2S,4R)-1-[2-[3-acetyl-5-(2-methylpyrimidin-5-yl)indazol-1-yl]acetyl]-N-(6-bromo-2-pyridinyl)-4-fluoropyrrolidine-2-carboxamide
- Canonical SMILES
- CC1=NC=C(C=N1)C2=CC3=C(C=C2)N(N=C3C(=O)C)CC(=O)N4C[C@@H](C[C@H]4C(=O)NC5=NC(=CC=C5)Br)F
- InChIKey
- PIBARDGJJAGJAJ-NQIIRXRSSA-N
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