Crisaborole

Overview

Crisaborole is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL484785).

API suppliers (11)

Suppliers of Crisaborole evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• CHANGZHOU PHARMACEUTICAL FACTORYChina1 active DMF GMP on record
• OPTIMUS DRUGS PRIVATE LTDIndia1 active DMF
• HONOUR LAB LTDIndia1 active DMF GMP on record
• VIRUPAKSHA ORGANICS LTDIndia1 active DMF
• MSN LIFE SCIENCES PRIVATE LIMITEDIndia1 active DMF GMP on record
• OLON SPAItaly1 active DMF GMP on record
• Macleods Pharmaceuticals Ltd.India1 active DMF GMP on record
• TAPI NL BVNetherlands1 active DMF
• ANHUI POLY PHARM CO LTDChina1 active DMF
• Jiangxi Synergy Pharmaceutical Co., LtdChina1 active DMF
• BIOPHORE INDIA PHARMACEUTICALS PVT LTD1 active DMF

Patent & exclusivity (US)

Per the FDA Orange Book (1 approved US product), the latest listed US patent on Crisaborole expires 20 Jul 2030 and exclusivity 3 Apr 2026. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

4-[(1-hydroxy-3H-2,1-benzoxaborol-5-yl)oxy]benzonitrile

Canonical SMILES

B1(C2=C(CO1)C=C(C=C2)OC3=CC=C(C=C3)C#N)O

InChIKey

USZAGAREISWJDP-UHFFFAOYSA-N