Crinecerfont

Overview

Crinecerfont is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL291657).

Patent & exclusivity (US)

Per the FDA Orange Book (4 approved US products), the latest listed US patent on Crinecerfont expires 12 Jan 2043 and exclusivity 13 Dec 2031. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-prop-2-ynyl-1,3-thiazol-2-amine

Canonical SMILES

CC1=C(C=C(C=C1)[C@H](CC2CC2)N(CC#C)C3=NC(=C(S3)C)C4=C(C=C(C(=C4)C)OC)Cl)F

InChIKey

IEAKXXNRGSLYTQ-DEOSSOPVSA-N