Colchicine

Overview

Colchicine is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL107).

API suppliers (13)

Suppliers of Colchicine evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• CHEMPLAST SANMAR LTDIndia1 active DMF
• CHEMICAL RESOURCES (CHERESO)India1 active DMF
• DR WILLMAR SCHWABE INDIA PVT LTDIndia1 active DMF
• ALKALOIDS BIOACTIVES PRIVATE LTDIndia1 active DMF
• PH HEALTH LTD1 active DMF
• SOLARA ACTIVE PHARMA SCIENCES LTDIndia1 active DMF GMP on record
• INDENA SPAItaly1 active DMF GMP on record
• SARV BIO LABS PVT LTD
• ALCHEM INTERNATIONAL LTDUnited States GMP on record
• ALKALOIDS CORPIndia
• ROUSSELL UCLAF
• VITAL LABORATORIES PVT LTD
• SM ORGANICS PRIVATE LTD

EU CEP holders (7)

Companies holding a valid EU Certificate of Suitability (CEP) for Colchicine, from the EDQM certification database. A CEP holder is a documented EU-market source of the substance — not necessarily the manufacturer — and these are not yet profiled in our directory.

Patent & exclusivity (US)

Per the FDA Orange Book (21 approved US products), the latest listed US patent on Colchicine expires 20 Dec 2037. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide

Canonical SMILES

CC(=O)N[C@H]1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC

InChIKey

IAKHMKGGTNLKSZ-INIZCTEOSA-N