Clotrimazole

Overview

Clotrimazole is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL104).

API suppliers (11)

Suppliers of Clotrimazole evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• AMOLI ORGANICS PVT LTD1 active DMF
• FIS FABBRICA ITALIANA SINTETICI SPAItaly1 active DMF GMP on record
• ERREGIERRE SPAItaly1 active DMF GMP on record
• OLON SPAItaly1 active DMF GMP on record
• SNJ LABS PVT LTDIndia1 active DMF
• SIFAVITOR SPA
• SHANGHAI ZHONGXI SUNVE PHARMACEUTICAL CO LTDChina
• Bayer PlcUnited Kingdom
• CORDEN PHARMA BERGAMO SPAItaly GMP on record
• CUTTER BIOLOGICAL DIV MILES LABORATORIES INC
• JIANGSU YUNYANG GROUP PHARMACEUTICAL CO LTD

EU CEP holders (5)

Companies holding a valid EU Certificate of Suitability (CEP) for Clotrimazole, from the EDQM certification database. A CEP holder is a documented EU-market source of the substance — not necessarily the manufacturer — and these are not yet profiled in our directory.

Patent & exclusivity (US)

Per the FDA Orange Book (15 approved US products), the latest listed US patent on Clotrimazole expires 26 May 2042 and exclusivity 26 Sept 2037. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

1-[(2-chlorophenyl)-diphenylmethyl]imidazole

Canonical SMILES

C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3Cl)N4C=CN=C4

InChIKey

VNFPBHJOKIVQEB-UHFFFAOYSA-N