Clindamycin

Overview

Clindamycin is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL1753).

API suppliers (14)

Suppliers of Clindamycin evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• Zhejiang Hisoar Pharmaceutical Co., Ltd.China2 active DMF
• Hubei Yitai Pharmaceutical Co., LtdChina2 active DMF
• CHONGQING CARELIFE PHARMACEUTICAL CO LTDChina2 active DMF
• Xinyu Pharmaceutical Co., Ltd.China2 active DMF
• ALCHYMARS ICM SM PRIVATE LTDIndia1 active DMF
• Zydus Lifesciences LimitedIndia1 active DMF GMP on record
• TRIFARMA SPAItaly1 active DMF GMP on record
• ZHEJIANG CANDORLY PHARMACEUTICAL CO LTD1 active DMF
• PHARMACIA AND UPJOHN CO LLC WHOLLY OWNED SUB OF PFIZER INC1 active DMF
• UNION QUIMICO FARMACEUTICA SA (UQUIFA SA)Spain1 active DMF
• SUZHOU NUMBER 4 PHARMACEUTICAL FACTORY
• PHARMACIA AND UPJOHN SUB PFIZER INC
• Aurobindo Pharma UsaUnited Kingdom
• HANGZHOU ZHONGMEI HUADONG PHARMACEUTICAL CO LTDChina

Patent & exclusivity (US)

Per the FDA Orange Book (77 approved US products), the latest listed US patent on Clindamycin expires 22 Sept 2036 and exclusivity 7 Dec 2029. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

(2S,4R)-N-[(1S,2S)-2-chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide

Canonical SMILES

CCC[C@@H]1C[C@H](N(C1)C)C(=O)N[C@@H]([C@@H]2[C@@H]([C@@H]([C@H]([C@H](O2)SC)O)O)O)[C@H](C)Cl

InChIKey

KDLRVYVGXIQJDK-AWPVFWJPSA-N