Clevidipine

Overview

Clevidipine is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL1237132).

API suppliers (2)

Suppliers of Clevidipine evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• CHEMWERTH INCFrance1 active DMF
• VERANOVA LPUnited Kingdom1 active DMF

Patent & exclusivity (US)

Per the FDA Orange Book (2 approved US products), the latest listed US patent on Clevidipine expires 10 Oct 2031. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

5-O-(butanoyloxymethyl) 3-O-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Canonical SMILES

CCCC(=O)OCOC(=O)C1=C(NC(=C(C1C2=C(C(=CC=C2)Cl)Cl)C(=O)OC)C)C

InChIKey

KPBZROQVTHLCDU-UHFFFAOYSA-N