Ciclesonide

Overview

Ciclesonide is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL2040682).

API suppliers (7)

Suppliers of Ciclesonide evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• DYNAMIT NOBEL GMBH EXPLOSIVSTOFF UND SYSTEMTECHNIKGermany1 active DMF GMP on record
• NEWCHEM SPAItaly1 active DMF GMP on record
• AARTI PHARMALABS LIMITEDIndia1 active DMF
• CORAL DRUGS PVT LTDIndia1 active DMF GMP on record
• STERLING SPAItaly1 active DMF GMP on record
• Cipla LimitedIndiaCEP GMP on record
• ALP PHARM BEIJING CO LTD

Patent & exclusivity (US)

Per the FDA Orange Book (3 approved US products), the latest listed US patent on Ciclesonide expires 1 Feb 2028. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

[2-[(1S,2S,4R,6R,8S,9S,11S,12S,13R)-6-cyclohexyl-11-hydroxy-9,13-dimethyl-16-oxo-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-8-yl]-2-oxoethyl] 2-methylpropanoate

Canonical SMILES

CC(C)C(=O)OCC(=O)[C@@]12[C@@H](C[C@@H]3[C@@]1(C[C@@H]([C@H]4[C@H]3CCC5=CC(=O)C=C[C@]45C)O)C)O[C@H](O2)C6CCCCC6

InChIKey

LUKZNWIVRBCLON-GXOBDPJESA-N