Cetirizine

Overview

Cetirizine is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL1000).

API suppliers (22)

Suppliers of Cetirizine evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• WAVELENGTH ENTERPRISES LTDIsrael2 active DMF GMP on record
• Sun Pharmaceutical Industries LimitedIndia1 active DMF GMP on record
• ORBION PHARMACEUTICALS PRIVATE LTDIndia1 active DMF GMP on record
• JUBILANT BIOSYS LTDIndia1 active DMF
• COSMA SPAItaly1 active DMF GMP on record
• SOLARA ACTIVE PHARMA SCIENCES LTDIndia1 active DMF GMP on record
• Ipca Laboratories LimitedIndia1 active DMF GMP on record
• CIMA LABORATORIES INC1 active DMF
• Taro Pharmaceutical Industries Ltd.Israel1 active DMF GMP on record
• GLOCHEM INDUSTRIES PRIVATE LTD1 active DMF
• PRAVEEN LABORATORIES PRIVATE LTD1 active DMF GMP on record
• Cipla USA, Inc.USA1 active DMF
• MATRIX PHARMACORP PRIVATE LTDIndia1 active DMF
• Unichem Laboratories Ltd.India1 active DMF GMP on record
• THINQ PHARMA-CRO LTDIndia1 active DMF
• Granules India LimitedIndia1 active DMF GMP on record
• SUPRIYA LIFESCIENCE LTDIndia1 active DMF
• DR REDDYS LABORATORIES LTD1 active DMF GMP on record
• GLOCHEM INDUSTRIES LTDIndia
• CAMBREX CHARLES CITY INCUnited States
• KV PHARMACEUTICAL CO
• SINTENOVO SA DE CV

Patent & exclusivity (US)

Per the FDA Orange Book (97 approved US products), the latest listed US patent on Cetirizine expires 9 Jan 2033. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]acetic acid

Canonical SMILES

C1CN(CCN1CCOCC(=O)O)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl

InChIKey

ZKLPARSLTMPFCP-UHFFFAOYSA-N