Ceftobiprole Medocaril Free Acid

Overview

Ceftobiprole Medocaril Free Acid is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL1652606).

Patent & exclusivity (US)

Per the FDA Orange Book (1 approved US product), the latest listed US patent on Ceftobiprole Medocaril Free Acid expires — and exclusivity 3 Apr 2034. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

(6R,7R)-7-[[(2E)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-hydroxyiminoacetyl]amino]-3-[(E)-[1-[(3R)-1-[(5-methyl-2-oxo-1,3-dioxol-4-yl)methoxycarbonyl]pyrrolidin-3-yl]-2-oxopyrrolidin-3-ylidene]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Canonical SMILES

CC1=C(OC(=O)O1)COC(=O)N2CC[C@H](C2)N3CC/C(=C\C4=C(N5[C@@H]([C@@H](C5=O)NC(=O)/C(=N/O)/C6=NSC(=N6)N)SC4)C(=O)O)/C3=O

InChIKey

HFTSMHTWUFCYMJ-FDNJTQOMSA-N