Cefixime

Overview

Cefixime is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL1541).

API suppliers (13)

Suppliers of Cefixime evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• Nectar Lifesciences LimitedIndia1 active DMF
• PURE AND CURE HEALTHCARE PRIVATE LTDIndia1 active DMF
• UNIMARK REMEDIES LTDIndia1 active DMF
• APITORIA PHARMA PRIVATE LTDIndia1 active DMF GMP on record
• COVALENT LABORATORIES PRIVATE LTDIndia1 active DMF
• Sandoz LtdUnited Kingdom1 active DMF
• Qilu Antibiotics Pharmaceutical Co., Ltd.China1 active DMF GMP on record
• DRUG MANUFACTURING COMPANY1 active DMF
• Zhejiang Apeloa Tospo Pharmaceutical Co., Ltd.China1 active DMF
• Lupin LimitedIndia1 active DMF GMP on record
• LEDERLE LABORATORIES
• SANDOZ PRIVATE LTDIndia
• Astellas Pharma Inc.Japan GMP on record

Patent & exclusivity (US)

Per the FDA Orange Book (15 approved US products), the latest listed US patent on Cefixime expires 14 Dec 2028. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(carboxymethoxyimino)acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Canonical SMILES

C=CC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)/C(=N\OCC(=O)O)/C3=CSC(=N3)N)SC1)C(=O)O

InChIKey

OKBVVJOGVLARMR-QSWIMTSFSA-N