Capivasertib

CAS 1143532-39-1 1 API supplierSmall Molecule

Overview

Capivasertib is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL2325741).

API suppliers (1)

Suppliers of Capivasertib evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

Where these suppliers are
Taiwan1

1 of 1 holds a GMP certificate on record in the EU or UK registers

Patent & exclusivity (US)

Per the FDA Orange Book (2 approved US products), the latest listed US patent on Capivasertib expires 16 Apr 2033 and exclusivity 12 Jun 2029. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name
4-amino-N-[(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Canonical SMILES
C1CN(CCC1(C(=O)N[C@@H](CCO)C2=CC=C(C=C2)Cl)N)C3=NC=NC4=C3C=CN4
InChIKey
JDUBGYFRJFOXQC-KRWDZBQOSA-N
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