Cangrelor

Overview

Cangrelor is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL334966).

API suppliers (3)

Suppliers of Cangrelor backed by a verifiable FDA Type II Drug Master File. Source: FDA quarterly DMF list.

• VERANOVA LP1 active DMF
• VERANOVA LP1 active DMF
• VERANOVA LP1 active DMF

Patent & exclusivity (US)

Per the FDA Orange Book (3 approved US products), the latest listed US patent on Cangrelor expires 9 Jul 2035. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

[dichloro-[[[(2R,3S,4R,5R)-3,4-dihydroxy-5-[6-(2-methylsulfanylethylamino)-2-(3,3,3-trifluoropropylsulfanyl)purin-9-yl]oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]methyl]phosphonic acid

Canonical SMILES

CSCCNC1=C2C(=NC(=N1)SCCC(F)(F)F)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)(C(P(=O)(O)O)(Cl)Cl)O)O)O

InChIKey

PAEBIVWUMLRPSK-IDTAVKCVSA-N