Calcipotriene

Overview

Calcipotriene is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL1200666).

API suppliers (9)

Suppliers of Calcipotriene evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• CHONGQING HUAPONT SHENGCHEM PHARMACEUTICAL CO LTDChina2 active DMF
• CERBIOS PHARMA SASwitzerland2 active DMF GMP on record
• Formosa Laboratories, Inc.Taiwan2 active DMF GMP on record
• Anhui Haoyuan Pharmaceutical Co., Ltd.China1 active DMF
• LEO PHARMA AS1 active DMF GMP on record
• TAPI NL BVNetherlands1 active DMF
• ALP PHARM BEIJING CO LTD1 active DMF
• NANJING HERON PHARMACEUTICAL CO LTD1 active DMF
• SAFC INCUnited States

Patent & exclusivity (US)

Per the FDA Orange Book (8 approved US products), the latest listed US patent on Calcipotriene expires 7 May 2028. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

trans-(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(E,2R,5S)-5-cyclopropyl-5-hydroxypent-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol

Canonical SMILES

C[C@H](/C=C/[C@H](C1CC1)O)[C@H]2CC[C@@H]\3[C@@]2(CCC/C3=C\C=C/4\C[C@H](C[C@@H](C4=C)O)O)C

InChIKey

LWQQLNNNIPYSNX-UROSTWAQSA-N