Calcifediol
Overview
Calcifediol is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL3544909).
API suppliers (3)
Suppliers of Calcifediol evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.
Country recorded for 2 of 3 suppliers.
2 of 3 hold a GMP certificate on record in the EU or UK registers
- Carbogen Amcis AGSwitzerland1 active DMF GMP on record
- Formosa Laboratories, Inc.Taiwan1 active DMF GMP on record
- SOLVAY DUPHAR BV
Patent & exclusivity (US)
Per the FDA Orange Book (1 approved US product), the latest listed US patent on Calcifediol expires 14 Mar 2034. Generic API sourcing typically opens up once these lapse.
Chemical identity
- IUPAC name
- (1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol;hydrate
- Canonical SMILES
- C[C@H](CCCC(C)(C)O)[C@H]1CC[C@@H]\2[C@@]1(CCC/C2=C\C=C/3\C[C@H](CCC3=C)O)C.O
- InChIKey
- WRLFSJXJGJBFJQ-WPUCQFJDSA-N
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