Bupropion

Overview

Bupropion is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL894).

API suppliers (22)

Suppliers of Bupropion evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• HIKAL LTDPakistan4 active DMF
• Sun Pharmaceutical Industries LimitedIndia2 active DMF GMP on record
• APITORIA PHARMA PRIVATE LTDIndia2 active DMF GMP on record
• Divis LaboratoriesIndia1 active DMF GMP on record
• MAHI DRUGS PRIVATE LIMITEDIndia1 active DMF
• Alembic Pharmaceuticals LimitedIndia1 active DMF GMP on record
• CHEMI SPAItaly1 active DMF GMP on record
• JUBILANT BIOSYS LTDIndia1 active DMF
• Zhejiang Supor Pharmaceuticals Co., LtdChina1 active DMF GMP on record
• Dipharma Francis SrlItaly1 active DMF GMP on record
• ALIVUS LIFE SCIENCES LTDIndia1 active DMF GMP on record
• Zhejiang Apeloa Jiayuan Pharmaceutical Co., Ltd.China1 active DMF
• Granules India LimitedIndia1 active DMF GMP on record
• Ipca Laboratories LimitedIndia1 active DMF GMP on record
• ERREGIERRE SPAItaly1 active DMF GMP on record
• Hetero Drugs LimitedIndia1 active DMF GMP on record
• Cadila Pharmaceuticals LimitedIndia1 active DMF GMP on record
• Zydus Lifesciences LimitedIndia1 active DMF GMP on record
• CHEMECA DRUGS PRIVATE LTDIndia1 active DMF
• UNION QUIMICO FARMACEUTICA SA (UQUIFA SA)Spain
• Seven Star Pharmaceutical Co., Ltd.Taiwan
• Lupin LimitedIndia GMP on record

Patent & exclusivity (US)

Per the FDA Orange Book (90 approved US products), the latest listed US patent on Bupropion expires 23 Aug 2028. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one

Canonical SMILES

CC(C(=O)C1=CC(=CC=C1)Cl)NC(C)(C)C

InChIKey

SNPPWIUOZRMYNY-UHFFFAOYSA-N