Brensocatib

Overview

Brensocatib is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL3900409).

Patent & exclusivity (US)

Per the FDA Orange Book (2 approved US products), the latest listed US patent on Brensocatib expires 21 Feb 2040 and exclusivity 12 Aug 2030. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

(2S)-N-[(1S)-1-cyano-2-[4-(3-methyl-2-oxo-1,3-benzoxazol-5-yl)phenyl]ethyl]-1,4-oxazepane-2-carboxamide

Canonical SMILES

CN1C2=C(C=CC(=C2)C3=CC=C(C=C3)C[C@@H](C#N)NC(=O)[C@@H]4CNCCCO4)OC1=O

InChIKey

AEXFXNFMSAAELR-RXVVDRJESA-N