Bendamustine

Overview

Bendamustine is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL487253).

API suppliers (14)

Suppliers of Bendamustine evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• DR REDDYS LABORATORIES LTD1 active DMF GMP on record
• BIOPHORE INDIA PHARMACEUTICALS PVT LTD1 active DMF
• SHILPA PHARMA LIFESCIENCES LTDIndia1 active DMF
• HERAEUS PRECIOUS METALS GMBH AND CO KGGermany1 active DMF
• CHONGQING HUAPONT PHARMACEUTICAL CO LTD1 active DMF
• Hetero Labs LimitedIndia1 active DMF GMP on record
• Emcure Pharmaceuticals LimitedIndia1 active DMF GMP on record
• OLON SPAItaly1 active DMF GMP on record
• NERPHARMA SRLItaly1 active DMF GMP on record
• MSN Laboratories Private LimitedIndia1 active DMF GMP on record
• NAVINTA LLCUnited States1 active DMF
• BEIJING HUIKANG BOYUAN CHEMICAL TECH CO LTDChina1 active DMF
• EUTICALS SPAItaly
• LIANYUNGANG RUNZHONG PHARMACEUTICAL CO LTDChina

Patent & exclusivity (US)

Per the FDA Orange Book (16 approved US products), the latest listed US patent on Bendamustine expires 29 Jul 2042. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid

Canonical SMILES

CN1C2=C(C=C(C=C2)N(CCCl)CCCl)N=C1CCCC(=O)O

InChIKey

YTKUWDBFDASYHO-UHFFFAOYSA-N