Bendamustine

Overview

Bendamustine is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL487253).

API suppliers (13)

Suppliers of Bendamustine backed by a verifiable FDA Type II Drug Master File. Source: FDA quarterly DMF list.

• HERAEUS PRECIOUS METALS GMBH AND CO KG1 active DMF
• CHONGQING CARELIFE PHARMACEUTICAL CO LTDChina1 active DMF
• Hetero Labs LimitedIndia1 active DMF
• CHONGQING CARELIFE PHARMACEUTICAL CO LTDChina1 active DMF
• Hetero Labs LimitedIndia1 active DMF
• Emcure Pharmaceuticals LimitedIndia1 active DMF
• MSN Laboratories Private LimitedIndia1 active DMF
• Dr. Reddy's Laboratories Ltd.India1 active DMF
• SHILPA PHARMA LIFESCIENCES LTD1 active DMF
• HERAEUS PRECIOUS METALS GMBH AND CO KG1 active DMF
• CHONGQING CARELIFE PHARMACEUTICAL CO LTDChina1 active DMF
• LIANYUNGANG RUNZHONG PHARMACEUTICAL CO LTDChina
• EUTICALS SPAItaly

Patent & exclusivity (US)

Per the FDA Orange Book (16 approved US products), the latest listed US patent on Bendamustine expires 28 Jul 2042. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid

Canonical SMILES

CN1C2=C(C=C(C=C2)N(CCCl)CCCl)N=C1CCCC(=O)O

InChIKey

YTKUWDBFDASYHO-UHFFFAOYSA-N