Belumosudil

Overview

Belumosudil is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL2005186).

Patent & exclusivity (US)

Per the FDA Orange Book (1 approved US product), the latest listed US patent on Belumosudil expires 14 Jul 2042 and exclusivity 16 Jul 2028. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

2-[3-[4-(1H-indazol-5-ylamino)quinazolin-2-yl]phenoxy]-N-propan-2-ylacetamide

Canonical SMILES

CC(C)NC(=O)COC1=CC=CC(=C1)C2=NC3=CC=CC=C3C(=N2)NC4=CC5=C(C=C4)NN=C5

InChIKey

GKHIVNAUVKXIIY-UHFFFAOYSA-N