Bedaquiline

CAS 843663-66-1Small Molecule

Overview

Bedaquiline is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL376488).

Patent & exclusivity (US)

Per the FDA Orange Book (2 approved US products), the latest listed US patent on Bedaquiline expires 19 Mar 2029 and exclusivity 21 Jun 2027. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name
(1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-naphthalen-1-yl-1-phenylbutan-2-ol
Canonical SMILES
CN(C)CC[C@@](C1=CC=CC2=CC=CC=C21)([C@H](C3=CC=CC=C3)C4=C(N=C5C=CC(=CC5=C4)Br)OC)O
InChIKey
QUIJNHUBAXPXFS-XLJNKUFUSA-N
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