Baloxavir Marboxil

CAS 1985606-14-1 6 API suppliersSmall Molecule

Overview

Baloxavir Marboxil is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL4297503).

API suppliers (6)

Suppliers of Baloxavir Marboxil evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

Where these suppliers are
China4India1

Country recorded for 5 of 6 suppliers.

2 of 6 hold a GMP certificate on record in the EU or UK registers

Patent & exclusivity (US)

Per the FDA Orange Book (7 approved US products), the latest listed US patent on Baloxavir Marboxil expires 21 Apr 2041 and exclusivity 19 Dec 2027. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name
[(3R)-2-[(11S)-7,8-difluoro-6,11-dihydrobenzo[c][1]benzothiepin-11-yl]-9,12-dioxo-5-oxa-1,2,8-triazatricyclo[8.4.0.03,8]tetradeca-10,13-dien-11-yl]oxymethyl methyl carbonate
Canonical SMILES
COC(=O)OCOC1=C2C(=O)N3CCOC[C@H]3N(N2C=CC1=O)[C@H]4C5=C(CSC6=CC=CC=C46)C(=C(C=C5)F)F
InChIKey
RZVPBGBYGMDSBG-GGAORHGYSA-N
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