Avatrombopag

Overview

Avatrombopag is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL2103883).

API suppliers (2)

Suppliers of Avatrombopag backed by a verifiable FDA Type II Drug Master File. Source: FDA quarterly DMF list.

• Zhejiang Hisun Pharmaceutical Co., Ltd.China2 active DMF
• TIANISH LABORATORIES PRIVATE LTDIndia1 active DMF

Patent & exclusivity (US)

Per the FDA Orange Book (2 approved US products), the latest listed US patent on Avatrombopag expires 28 Jul 2027 and exclusivity 24 Jul 2032. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

1-[3-chloro-5-[[4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)-1,3-thiazol-2-yl]carbamoyl]-2-pyridinyl]piperidine-4-carboxylic acid

Canonical SMILES

C1CCC(CC1)N2CCN(CC2)C3=C(N=C(S3)NC(=O)C4=CC(=C(N=C4)N5CCC(CC5)C(=O)O)Cl)C6=CC(=CS6)Cl

InChIKey

OFZJKCQENFPZBH-UHFFFAOYSA-N