Avacopan

Overview

Avacopan is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL3989871).

API suppliers (3)

Suppliers of Avacopan backed by a verifiable FDA Type II Drug Master File. Source: FDA quarterly DMF list.

• MAITHRI DRUGS PRIVATE LTDIndia1 active DMF
• POSH CHEMICALS PRIVATE LTDIndia1 active DMF
• Hetero Labs LimitedIndia1 active DMF

Patent & exclusivity (US)

Per the FDA Orange Book (1 approved US product), the latest listed US patent on Avacopan expires 27 Nov 2039 and exclusivity 7 Oct 2028. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

(2R,3S)-2-[4-(cyclopentylamino)phenyl]-1-(2-fluoro-6-methylbenzoyl)-N-[4-methyl-3-(trifluoromethyl)phenyl]piperidine-3-carboxamide

Canonical SMILES

CC1=C(C(=CC=C1)F)C(=O)N2CCC[C@@H]([C@@H]2C3=CC=C(C=C3)NC4CCCC4)C(=O)NC5=CC(=C(C=C5)C)C(F)(F)F

InChIKey

PUKBOVABABRILL-YZNIXAGQSA-N