Artesunate

Overview

Artesunate is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL361497).

API suppliers (6)

Suppliers of Artesunate backed by a verifiable FDA Type II Drug Master File. Source: FDA quarterly DMF list.

• SOLARA ACTIVE PHARMA SCIENCES LTD1 active DMF
• OLON SPAItaly1 active DMF
• SOLARA ACTIVE PHARMA SCIENCES LTD1 active DMF
• Ipca Laboratories LimitedIndia
• HUVEPHARMA ITALIA SRL
• Cipla USA, Inc.USA

Patent & exclusivity (US)

Per the FDA Orange Book (1 approved US product), the latest listed US patent on Artesunate expires 16 Feb 2044 and exclusivity 25 May 2027. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

4-oxo-4-[[(1R,4S,5R,8S,9R,10S,12R,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-yl]oxy]butanoic acid

Canonical SMILES

C[C@@H]1CC[C@H]2[C@H]([C@@H](O[C@H]3[C@@]24[C@H]1CC[C@](O3)(OO4)C)OC(=O)CCC(=O)O)C

InChIKey

FIHJKUPKCHIPAT-AHIGJZGOSA-N