Artesunate

CAS 88495-63-0 5 API suppliersSmall Molecule

Overview

Artesunate is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL361497).

API suppliers (5)

Suppliers of Artesunate evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

Where these suppliers are
India2Italy1USA1

Country recorded for 4 of 5 suppliers.

4 of 5 hold a GMP certificate on record in the EU or UK registers

Patent & exclusivity (US)

Per the FDA Orange Book (1 approved US product), the latest listed US patent on Artesunate expires 16 Feb 2044 and exclusivity 26 May 2027. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name
4-oxo-4-[[(1R,4S,5R,8S,9R,10S,12R,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-yl]oxy]butanoic acid
Canonical SMILES
C[C@@H]1CC[C@H]2[C@H]([C@@H](O[C@H]3[C@@]24[C@H]1CC[C@](O3)(OO4)C)OC(=O)CCC(=O)O)C
InChIKey
FIHJKUPKCHIPAT-AHIGJZGOSA-N
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