Aprocitentan

CAS 1103522-45-7Small Molecule

Overview

Aprocitentan is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL2165326).

Patent & exclusivity (US)

Per the FDA Orange Book (1 approved US product), the latest listed US patent on Aprocitentan expires 26 Jul 2038 and exclusivity 22 Mar 2029. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name
5-(4-bromophenyl)-4-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-6-(sulfamoylamino)pyrimidine
Canonical SMILES
C1=CC(=CC=C1C2=C(N=CN=C2OCCOC3=NC=C(C=N3)Br)NS(=O)(=O)N)Br
InChIKey
DKULOVKANLVDEA-UHFFFAOYSA-N
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