Apomorphine

Overview

Apomorphine is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL53).

API suppliers (9)

Suppliers of Apomorphine backed by a verifiable FDA Type II Drug Master File. Source: FDA quarterly DMF list.

• FRANCOPIA A EUROAPI CO1 active DMF
• MACFARLAN SMITH LTD1 active DMF
• MACFARLAN SMITH LTD1 active DMF
• FRANCOPIA A EUROAPI CO1 active DMF
• MACFARLAN SMITH LTD1 active DMF
• MACFARLAN SMITH LTD1 active DMF
• SIGMA F AND D DIV LTD
• DIOSYNTH BV
• LABORATOIRE AGUETTANT PARC SCIENTIFIC TONY GARNIER RUE ALEXANDER FLEMMING

Patent & exclusivity (US)

Per the FDA Orange Book (3 approved US products), the latest listed US patent on Apomorphine expires — and exclusivity 3 Feb 2028. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

(6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol

Canonical SMILES

CN1CCC2=C3[C@H]1CC4=C(C3=CC=C2)C(=C(C=C4)O)O

InChIKey

VMWNQDUVQKEIOC-CYBMUJFWSA-N