Angiotensin Ii

Overview

Angiotensin Ii is a protein active pharmaceutical ingredient (ChEMBL CHEMBL408403).

API suppliers (3)

Suppliers of Angiotensin Ii evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• BCN PEPTIDES SASpain1 active DMF GMP on record
• PENINSULA LABS INC
• BACHEM CALIFORNIA

Patent & exclusivity (US)

Per the FDA Orange Book (3 approved US products), the latest listed US patent on Angiotensin Ii expires 6 Jan 2037. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

(3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[(2S)-2-[[(1S)-1-carboxy-2-phenylethyl]carbamoyl]pyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-oxobutanoic acid

Canonical SMILES

CC[C@H](C)[C@@H](C(=O)N[C@@H](CC1=CN=CN1)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)O)NC(=O)[C@H](CC4=CC=C(C=C4)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(=O)O)N

InChIKey

CZGUSIXMZVURDU-JZXHSEFVSA-N