Alcaftadine
Overview
Alcaftadine is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL1201747).
API suppliers (4)
Suppliers of Alcaftadine evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.
1 of 4 holds a GMP certificate on record in the EU or UK registers
- CURIA SPAIN SAUSpain1 active DMF GMP on record
- Neuland Laboratories LimitedIndia1 active DMF
- APICORE PHARMACEUTICALS PRIVATE LIMITEDIndia1 active DMF
- ENALTEC LABS PRIVATE LTDIndia
Patent & exclusivity (US)
Per the FDA Orange Book (3 approved US products), the latest listed US patent on Alcaftadine expires 23 Dec 2027. Generic API sourcing typically opens up once these lapse.
Chemical identity
- IUPAC name
- 11-(1-methylpiperidin-4-ylidene)-5,6-dihydroimidazo[2,1-b][3]benzazepine-3-carbaldehyde
- Canonical SMILES
- CN1CCC(=C2C3=CC=CC=C3CCN4C2=NC=C4C=O)CC1
- InChIKey
- MWTBKTRZPHJQLH-UHFFFAOYSA-N
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