Aficamten

Overview

Aficamten is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL4847050).

Patent & exclusivity (US)

Per the FDA Orange Book (4 approved US products), the latest listed US patent on Aficamten expires 15 Jul 2042 and exclusivity 19 Dec 2030. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

N-[(1R)-5-(5-ethyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl]-1-methylpyrazole-4-carboxamide

Canonical SMILES

CCC1=NC(=NO1)C2=CC3=C(C=C2)[C@@H](CC3)NC(=O)C4=CN(N=C4)C

InChIKey

IOVAZWDIRCRMTM-OAHLLOKOSA-N