Vortioxetine

Overview

Vortioxetine is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL2104993).

API suppliers (11)

Suppliers of Vortioxetine evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• MSN PHARMACHEM PRIVATE LTDIndia2 active DMF
• Viyash Scientific LtdIndia1 active DMF GMP on record
• RAKS PHARMA PVT LTDIndia1 active DMF
• Dipharma Francis SrlItaly1 active DMF GMP on record
• Macleods Pharmaceuticals Ltd.India1 active DMF GMP on record
• SIGMAPHARM LABORATORIES LLCUnited States1 active DMF
• Zydus Lifesciences LimitedIndia1 active DMF GMP on record
• MEGAFINE PHARMA P LTDIndia1 active DMF
• METROCHEM API PRIVATE LTDIndia1 active DMF
• H LUNDBECK AS1 active DMF
• MOREPEN LABORATORIES LTDIndia1 active DMF GMP on record

Patent & exclusivity (US)

Per the FDA Orange Book (3 approved US products), the latest listed US patent on Vortioxetine expires 21 Sept 2032 and exclusivity 23 Feb 2027. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

1-[2-(2,4-dimethylphenyl)sulfanylphenyl]piperazine

Canonical SMILES

CC1=CC(=C(C=C1)SC2=CC=CC=C2N3CCNCC3)C

InChIKey

YQNWZWMKLDQSAC-UHFFFAOYSA-N