Olopatadine

Overview

Olopatadine is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL1189432).

API suppliers (12)

Suppliers of Olopatadine evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• CURIA SPAIN SAUSpain2 active DMF GMP on record
• ALIVUS LIFE SCIENCES LTDIndia1 active DMF GMP on record
• INDOCO REMEDIES LTDIndia1 active DMF GMP on record
• USV PRIVATE LTDIndia1 active DMF GMP on record
• MSN Laboratories Private LimitedIndia1 active DMF GMP on record
• PCASFrance1 active DMF GMP on record
• KYOWA PHARMA CHEMICAL CO LTDJapan1 active DMF GMP on record
• Sun Pharmaceutical Industries LimitedIndia1 active DMF GMP on record
• FDC LimitedIndia1 active DMF GMP on record
• Kyowa Kirin Co., Ltd.Japan GMP on record
• CHUNGHWA CHEMICAL SYNTHESIS AND BIOTECH CO LTD GMP on record
• Apotex Pharmachem India Pvt. Ltd.India

Patent & exclusivity (US)

Per the FDA Orange Book (25 approved US products), the latest listed US patent on Olopatadine expires 19 May 2032. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

2-[(11Z)-11-[3-(dimethylamino)propylidene]-6H-benzo[c][1]benzoxepin-2-yl]acetic acid

Canonical SMILES

CN(C)CC/C=C\1/C2=CC=CC=C2COC3=C1C=C(C=C3)CC(=O)O

InChIKey

JBIMVDZLSHOPLA-LSCVHKIXSA-N