Lenvatinib
Overview
Lenvatinib is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL1289601).
API suppliers (4)
Suppliers of Lenvatinib evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.
Country recorded for 3 of 4 suppliers.
4 of 4 hold a GMP certificate on record in the EU or UK registers
- MSN Laboratories Private LimitedIndia2 active DMF GMP on record
- DR REDDYS LABORATORIES LTD2 active DMF GMP on record
- OLON SPAItaly1 active DMF GMP on record
- Zhejiang Ausun Pharmaceutical Co., Ltd.China1 active DMF GMP on record
Patent & exclusivity (US)
Per the FDA Orange Book (2 approved US products), the latest listed US patent on Lenvatinib expires 15 Nov 2038 and exclusivity 3 Oct 2027. Generic API sourcing typically opens up once these lapse.
Chemical identity
- IUPAC name
- 4-[3-chloro-4-(cyclopropylcarbamoylamino)phenoxy]-7-methoxyquinoline-6-carboxamide
- Canonical SMILES
- COC1=CC2=NC=CC(=C2C=C1C(=O)N)OC3=CC(=C(C=C3)NC(=O)NC4CC4)Cl
- InChIKey
- WOSKHXYHFSIKNG-UHFFFAOYSA-N
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