Fezolinetant

Overview

Fezolinetant is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL3608680).

API suppliers (4)

Suppliers of Fezolinetant backed by a verifiable FDA Type II Drug Master File. Source: FDA quarterly DMF list.

• MOEHS IBERICA SLSpain1 active DMF
• SHANDONG XINHUA PHARMACEUTICAL CO LTDChina1 active DMF
• MAHIMA LIFE SCIENCES PRIVATE LTDIndia1 active DMF
• AMI LIFESCIENCES PRIVATE LTDIndia1 active DMF

Patent & exclusivity (US)

Per the FDA Orange Book (1 approved US product), the latest listed US patent on Fezolinetant expires 28 Mar 2034 and exclusivity 12 May 2028. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

(4-fluorophenyl)-[(8R)-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]methanone

Canonical SMILES

C[C@@H]1C2=NN=C(N2CCN1C(=O)C3=CC=C(C=C3)F)C4=NC(=NS4)C

InChIKey

PPSNFPASKFYPMN-SECBINFHSA-N