Fexofenadine

Overview

Fexofenadine is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL914).

API suppliers (15)

Suppliers of Fexofenadine evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• Dipharma Francis SrlItaly2 active DMF GMP on record
• MATRIX PHARMACORP PRIVATE LTDIndia1 active DMF
• VIRUPAKSHA ORGANICS LTDIndia1 active DMF
• SYNTHIMED LABS PRIVATE LIMITEDIndia1 active DMF GMP on record
• APITORIA PHARMA PRIVATE LTDIndia1 active DMF GMP on record
• VASUDHA PHARMA CHEM LTDIndia1 active DMF
• MOREPEN LABORATORIES LTDIndia1 active DMF GMP on record
• THINQ PHARMA-CRO LTDIndia1 active DMF
• CHEMECA DRUGS PRIVATE LTDIndia1 active DMF
• DR REDDYS LABORATORIES LTD1 active DMF GMP on record
• Granules India LimitedIndia1 active DMF GMP on record
• RA CHEM PHARMA LTDIndia
• Cipla USA, Inc.USA
• Sanofi-aventis Deutschland GmbhGermany GMP on record
• Sun Pharmaceutical Industries LimitedIndia GMP on record

Patent & exclusivity (US)

Per the FDA Orange Book (40 approved US products), the latest listed US patent on Fexofenadine expires 2 Aug 2030. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

2-[4-[1-hydroxy-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butyl]phenyl]-2-methylpropanoic acid

Canonical SMILES

CC(C)(C1=CC=C(C=C1)C(CCCN2CCC(CC2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O)O)C(=O)O

InChIKey

RWTNPBWLLIMQHL-UHFFFAOYSA-N