Epoprostenol

Overview

Epoprostenol is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL1139).

API suppliers (3)

Suppliers of Epoprostenol backed by a verifiable FDA Type II Drug Master File. Source: FDA quarterly DMF list.

• PHARMACIA AND UPJOHN CO WHOLLY OWNED SUB PFIZER INC1 active DMF
• PHARMACIA AND UPJOHN CO WHOLLY OWNED SUB PFIZER INC1 active DMF
• ALIVUS LIFE SCIENCES LTD

Patent & exclusivity (US)

Per the FDA Orange Book (10 approved US products), the latest listed US patent on Epoprostenol expires 15 Mar 2027. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

(5Z)-5-[(3aR,4R,5R,6aS)-5-hydroxy-4-[(E,3S)-3-hydroxyoct-1-enyl]-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-2-ylidene]pentanoic acid

Canonical SMILES

CCCCC[C@@H](/C=C/[C@H]1[C@@H](C[C@H]2[C@@H]1C/C(=C/CCCC(=O)O)/O2)O)O

InChIKey

KAQKFAOMNZTLHT-OZUDYXHBSA-N