Epoprostenol
Overview
Epoprostenol is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL1139).
API suppliers (3)
Suppliers of Epoprostenol evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.
Country recorded for 2 of 3 suppliers.
1 of 3 holds a GMP certificate on record in the EU or UK registers
- MSN Laboratories Private LimitedIndia1 active DMF GMP on record
- PHARMACIA AND UPJOHN SUB PFIZER INC1 active DMF
- Sai Life Sciences LimitedIndia
Patent & exclusivity (US)
Per the FDA Orange Book (8 approved US products), the latest listed US patent on Epoprostenol expires 15 Mar 2027. Generic API sourcing typically opens up once these lapse.
Chemical identity
- IUPAC name
- (5Z)-5-[(3aR,4R,5R,6aS)-5-hydroxy-4-[(E,3S)-3-hydroxyoct-1-enyl]-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-2-ylidene]pentanoic acid
- Canonical SMILES
- CCCCC[C@@H](/C=C/[C@H]1[C@@H](C[C@H]2[C@@H]1C/C(=C/CCCC(=O)O)/O2)O)O
- InChIKey
- KAQKFAOMNZTLHT-OZUDYXHBSA-N
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